Articles

New Insights into Polymyxins: How Last-Resort Antibiotics Shatter Bacterial Defenses

September 29, 2025
AntibioticsBacteriaHealthcareMedicineInfectionsResearchSciencePublic Health

Researchers unveil how polymyxins, key last-resort antibiotics, dismantle bacterial defenses by inducing cells to overproduce and shed their protective armor. However, these antibiotics are only effective against active bacteria, leaving dormant cells unharmed. These findings may explain recurrent infections and lead to new methods to awaken bacteria for successful treatment.

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